STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mreCCell shape-determining protein MreC; Involved in formation and maintenance of cell shape. (286 aa)    
Predicted Functional Partners:
mreB
Cell wall structural complex MreBCD, actin-like component MreB; Function of homologous gene experimentally demonstrated in an other organism; structure.
 
 
 0.996
mreD
Rod shape-determining protein MreD.
  
 
 0.990
mrdA
Penicillin-binding protein 2.
 
 
 0.978
mrdB
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
  
 0.966
radC
Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0758 family.
  
  
 0.842
CEM61172.1
Tetratricopeptide repeat protein.
       0.791
CEM62999.1
Penicillin-binding protein, transpeptidase domain protein.
 
 
 0.703
CEM63035.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
 
 
 0.679
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
  
 0.664
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.661
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.