Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pdxB4-phosphoerythronate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (331 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.805
nifJ
Pyruvate-flavodoxin oxidoreductase.
  
  
 0.708
gltS
Sodium/glutamate symport carrier protein; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
       0.645
CEM62821.1
Putative dipeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
    0.581
CEM63013.1
Peptidase, C69 family (fragment).
   
    0.581
CEM63014.1
Putative dipeptidase B (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
    0.581
CEM61966.1
Rubredoxin.
  
 
 0.580
gpmA
Phosphoglyceromutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
 0.568
msrB
Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.562
CEM62395.1
Putative Pyruvate kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.529
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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