STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trxBThioredoxin reductase. (307 aa)    
Predicted Functional Partners:
selD
Selenide, water dikinase.
     
 0.914
mdeA
Methionine gamma-lyase.
   
 
 0.909
csd
Putative cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
  
 
 0.906
CEM61144.1
Putative selenate reductase, YgfK subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
    
  0.902
trxA
Thioredoxin; Belongs to the thioredoxin family.
 
 
 0.821
CEM61404.1
Glycosyl hydrolase family 3 N-terminal domain protein.
     
 0.780
CEM61403.1
Acetyltransferase, GNAT family.
       0.775
ahpC
Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 
 0.742
CEM61310.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein (modular protein).
 
  
 0.592
CEM61005.1
Pyridine nucleotide-disulfide oxidoreductase (fragment).
  
 
 0.564
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.