Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CEM61440.1Leucine Rich Repeat protein. (265 aa)    
Predicted Functional Partners:
CEM61784.1
Diguanylate cyclase (GGDEF) domain protein (fragment).
  
  
 0.714
CEM62587.1
Putative ankyrin repeat-containing protein TP_0502; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
 
 0.667
CEM63123.1
Ankyrin repeat protein.
   
 
 0.667
CEM61310.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein (modular protein).
  
  
 0.604
CEM61439.1
Hypothetical protein; No homology to any previously reported sequences.
       0.572
nnrE
YjeF domain protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
       0.505
CEM61299.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
   
0.434
CEM61007.1
Response regulator receiver domain protein.
  
  
 0.406
CEM63322.1
HD domain protein.
     
 0.406
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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