close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEM61737.1Oxidoreductase, short chain dehydrogenase/reductase family protein. (253 aa)    
Predicted Functional Partners:
fruK
1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family.
  
  
 0.875
gatA
Glutamyl-tRNA(Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
  
 
 0.828
CEM60452.1
Peptidyl-prolyl cis-trans isomerase.
  
 
 0.818
sbcD
Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
  
 
 
 0.777
nifJ
Pyruvate-flavodoxin oxidoreductase.
   
 
 0.773
queD
6-carboxy-5,6,7,8-tetrahydropterin synthase.
  
 
 0.770
CEM61966.1
Rubredoxin.
  
 0.770
CEM63087.1
Pyridine nucleotide-disulfide oxidoreductase (fragment).
   
 
 0.740
CEM62178.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
  
 0.738
lacZ
Beta-galactosidase; Belongs to the glycosyl hydrolase 2 family.
  
  
 0.738
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.