STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (498 aa)    
Predicted Functional Partners:
glpF
Putative glycerol uptake facilitator protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the MIP/aquaporin (TC 1.A.8) family.
 
 
 0.989
CEM62560.1
PTS system, beta-glucoside-specific, IIABC component.
  
 
 0.876
rdgB
Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
      0.718
CEM60381.1
Glycerophosphodiester phosphodiesterase family protein (modular protein).
  
  
 0.693
glpQ
Periplasmic glycerophosphodiester phosphodiesterase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.693
ydbK
Putative 2-oxoacid-flavodoxin fused oxidoreductase:conserved protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.674
CEM60829.1
Pyridoxal-dependent decarboxylase, pyridoxal binding domain protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
   
 0.608
CEM61748.1
FAD dependent oxidoreductase.
  
  
 0.600
CEM60452.1
Peptidyl-prolyl cis-trans isomerase.
   
 0.535
CEM61750.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.532
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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