Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CEM61761.1HAD hydrolase, family IA, variant 1. (233 aa)    
Predicted Functional Partners:
CEM61762.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
     0.814
CEM63003.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
    0.635
cmk
Cytidylate kinase.
 
     0.595
CEM62056.1
Phosphoribosyl transferase domain protein.
 
   
 0.543
CEM61816.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.524
CEM61330.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
     0.508
pheS
Phenylalanine--tRNA ligase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
 
     0.450
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.448
CEM62891.1
Inosine 5-monophosphate dehydrogenase.
     
 0.439
upp
Putative uracil phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
     0.425
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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