Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pepTPeptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. (413 aa)    
Predicted Functional Partners:
CEM62098.1
Putative GTP cyclohydrolase 1 type 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
    0.547
CEM61024.1
Creatinase.
  
 
 0.487
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
       0.459
CEM62891.1
Inosine 5-monophosphate dehydrogenase.
   
 
 0.448
fliD
Flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
   
   0.425
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
  
 0.418
CEM61509.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.410
CEM61510.1
Hypothetical protein; No homology to any previously reported sequences.
       0.410
CEM61511.1
Hypothetical protein; No homology to any previously reported sequences.
       0.410
pepF
Oligoendopeptidase F.
  
  
 0.400
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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