Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CEM61526.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (330 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 
 0.678
ptsH
Phosphocarrier protein HPr.
   
 
 0.581
ptsH-2
Phosphocarrier protein HPr.
   
 
 0.581
ptsH-3
Phosphocarrier protein HPr.
   
 
 0.581
CEM62891.1
Inosine 5-monophosphate dehydrogenase.
    
 
 0.576
ribBA
Riboflavin biosynthesis protein RibBA (Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
   0.553
CEM61527.1
ABC transporter, ATP-binding protein.
       0.551
fruA
PTS system fructose-specific EIIABC component.
     
 0.490
fruA-2
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; PTS system fructose-specific EIIABC component (Includes: Fructose-specific phosphotransferase enzyme IIA component; Fructose-specific phosphotransferase enzyme IIB component; Fructose permease IIC component).
     
 0.490
CEM61310.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein (modular protein).
    
 
 0.475
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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