Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
IolGOxidoreductase, NAD-binding domain protein. (337 aa)    
Predicted Functional Partners:
iolE
Inosose dehydratase.
 
 
 0.984
yrbE
Uncharacterized oxidoreductase YrbE.
  
  
 
0.921
iolD
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; Belongs to the TPP enzyme family.
 
  
 0.858
CEM63167.1
Myo-inositol catabolism protein IolB.
 
  
 0.808
rbsC-2
D-ribose transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the binding-protein-dependent transport system permease family.
  
    0.645
mglA-2
Fused methyl-galactoside transporter subunits of ABC superfamily: ATP-binding components; Function of homologous gene experimentally demonstrated in an other organism; transporter.
  
  
 0.584
iolC
5-dehydro-2-deoxygluconokinase.
 
  
 0.564
iolA
Methylmalonate semialdehyde dehydrogenase (acylating) 2.
  
  
 0.435
CEM61540.1
Sugar-binding domain protein.
 
  
 0.425
ydbK
Putative 2-oxoacid-flavodoxin fused oxidoreductase:conserved protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.412
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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