Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
iolEInosose dehydratase. (298 aa)    
Predicted Functional Partners:
iolD
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; Belongs to the TPP enzyme family.
 
 
 0.994
IolG
Oxidoreductase, NAD-binding domain protein.
 
 
 0.984
yrbE
Uncharacterized oxidoreductase YrbE.
 
 
 0.982
CEM63167.1
Myo-inositol catabolism protein IolB.
 
  
 0.926
iolC
5-dehydro-2-deoxygluconokinase.
 
  
 0.822
CEM61540.1
Sugar-binding domain protein.
 
    0.540
CEM63306.1
Putative shikimate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.508
CEM62364.1
Oxidoreductase, NAD-binding domain protein.
 
  
 0.421
iolA
Methylmalonate semialdehyde dehydrogenase (acylating) 2.
 
  
 0.405
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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