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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iolD3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; Belongs to the TPP enzyme family. (641 aa)    
Predicted Functional Partners:
iolE
Inosose dehydratase.
 
 0.998
CEM63167.1
Myo-inositol catabolism protein IolB.
 
 
 0.997
IolG
Oxidoreductase, NAD-binding domain protein.
 
  
 0.952
yrbE
Uncharacterized oxidoreductase YrbE.
 
  
 0.948
iolC
5-dehydro-2-deoxygluconokinase.
 
  
 0.918
ulaE
L-xylulose 5-phosphate 3-epimerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.832
CEM62364.1
Oxidoreductase, NAD-binding domain protein.
 
  
 0.830
iolA
Methylmalonate semialdehyde dehydrogenase (acylating) 2.
  
 0.823
CEM60427.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
  
 0.782
adhE
Fused acetaldehyde-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.691
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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