Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
iolD3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; Belongs to the TPP enzyme family. (641 aa)    
Predicted Functional Partners:
CEM63167.1
Myo-inositol catabolism protein IolB.
 
 
 0.998
iolE
Inosose dehydratase.
 
 
 0.994
IolG
Oxidoreductase, NAD-binding domain protein.
 
  
 0.858
yrbE
Uncharacterized oxidoreductase YrbE.
 
  
 0.845
iolC
5-dehydro-2-deoxygluconokinase.
 
  
 0.842
iolA
Methylmalonate semialdehyde dehydrogenase (acylating) 2.
  
 0.670
rbsB
D-ribose transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
  
 0.543
CEM61540.1
Sugar-binding domain protein.
  
 0.520
ulaE
L-xylulose 5-phosphate 3-epimerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.499
CEM62364.1
Oxidoreductase, NAD-binding domain protein.
 
  
 0.493
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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