Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
glxKGlycerate kinase; Belongs to the glycerate kinase type-1 family. (380 aa)    
Predicted Functional Partners:
ywdH
Putative aldehyde dehydrogenase YwdH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the aldehyde dehydrogenase family.
   
 
 0.904
gpmA
Phosphoglyceromutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
     
 0.903
CEM61552.1
Transporter, gluconate:H+ symporter family.
  
  
 0.875
yjgF
Ketoacid-binding protein; Function of homologous gene experimentally demonstrated in an other organism; putative enzyme.
      0.666
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
      0.526
CEM62856.1
Transporter, gluconate:H+ symporter family.
  
  
 0.519
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.486
CEM61551.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.429
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.