Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rsmERibosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (249 aa)    
Predicted Functional Partners:
CEM61560.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.773
CEM61558.1
Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function.
       0.655
dnaJ
Chaperone Hsp40, co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...]
 
   0.495
CEM62135.1
Pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.483
fkpA
FKBP-type peptidyl-prolyl cis-trans isomerase FkpA.
  
     0.481
hslO
Chaperonin HslO.
 
     0.434
CEM61310.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein (modular protein).
     
 0.419
CEM61039.1
DnaJ domain protein.
  
   0.416
CEM61313.1
DnaJ domain protein.
  
   0.416
CEM62975.1
DnaJ domain protein.
  
   0.416
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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