Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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[Homology]
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csrACarbon storage regulator homolog; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (72 aa)    
Predicted Functional Partners:
fliW
Flagellar assembly factor FliW; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
 
 
 0.998
flgK
Flagellar hook-associated protein FlgK.
 
  
 0.874
flgL
Flagellar hook-associated protein 3.
  
  
 0.841
fliF
Flagellar M-ring protein.
  
  
 0.718
fliN
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
  
   0.688
CEM61310.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein (modular protein).
  
  
 0.686
fliS
Flagellar protein FliS.
 
  
 0.684
flaB-2
Flagellar filament 31 kDa core protein; Component of the core of the flagella. Belongs to the bacterial flagellin family.
 
  
 0.683
flaB-3
Flagellar filament 33 kDa core protein; Component of the core of the flagella. Belongs to the bacterial flagellin family.
 
  
 0.680
flaB
Flagellar filament 34.5 kDa core protein; Component of the core of the flagella. Belongs to the bacterial flagellin family.
 
  
 0.678
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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