Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CEM61573.1Inosine-uridine preferring nucleoside hydrolase. (342 aa)    
Predicted Functional Partners:
rbsK
Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 0.870
CEM60804.1
Kinase, PfkB family.
 
  
 0.689
CEM61572.1
Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.616
CEM62056.1
Phosphoribosyl transferase domain protein.
     
 0.581
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.540
CEM61574.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.483
CEM61146.1
Putative permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
    0.474
CEM60437.1
Phosphoribulokinase/uridine kinase family protein.
  
 
 0.451
flaG
FlaG protein (fragment).
    
   0.405
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
Server load: low (14%) [HD]