node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CEM60679.1 | tsaD | TPHV1_10347 | TPHV1_110092 | Putative Sua5/YciO/YrdC/YwlC family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the SUA5 family. | tRNA N6-adenosine threonylcarbamoyltransferase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.540 |
CEM60679.1 | tsaE | TPHV1_10347 | TPHV1_20121 | Putative Sua5/YciO/YrdC/YwlC family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the SUA5 family. | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | 0.426 |
CEM60679.1 | yeaZ | TPHV1_10347 | TPHV1_20120 | Putative Sua5/YciO/YrdC/YwlC family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the SUA5 family. | Universal bacterial protein YeaZ. | 0.501 |
CEM61059.1 | yeaZ | TPHV1_140007 | TPHV1_20120 | Biotin--(acetyl-CoA-carboxylase) ligase. | Universal bacterial protein YeaZ. | 0.692 |
CEM61581.1 | CEM61582.1 | TPHV1_20118 | TPHV1_20119 | Endonuclease/exonuclease/phosphatase family protein. | HD domain protein. | 0.615 |
CEM61581.1 | tsaE | TPHV1_20118 | TPHV1_20121 | Endonuclease/exonuclease/phosphatase family protein. | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | 0.546 |
CEM61581.1 | yeaZ | TPHV1_20118 | TPHV1_20120 | Endonuclease/exonuclease/phosphatase family protein. | Universal bacterial protein YeaZ. | 0.548 |
CEM61582.1 | CEM61581.1 | TPHV1_20119 | TPHV1_20118 | HD domain protein. | Endonuclease/exonuclease/phosphatase family protein. | 0.615 |
CEM61582.1 | tsaE | TPHV1_20119 | TPHV1_20121 | HD domain protein. | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | 0.762 |
CEM61582.1 | uvrC | TPHV1_20119 | TPHV1_20122 | HD domain protein. | UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.498 |
CEM61582.1 | yeaZ | TPHV1_20119 | TPHV1_20120 | HD domain protein. | Universal bacterial protein YeaZ. | 0.762 |
CEM61606.1 | yeaZ | TPHV1_20143 | TPHV1_20120 | Uracil-DNA glycosylase, family 4. | Universal bacterial protein YeaZ. | 0.673 |
tilS | truA | TPHV1_180055 | TPHV1_240025 | tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.659 |
tilS | tsaE | TPHV1_180055 | TPHV1_20121 | tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | 0.413 |
tilS | yeaZ | TPHV1_180055 | TPHV1_20120 | tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | Universal bacterial protein YeaZ. | 0.557 |
truA | tilS | TPHV1_240025 | TPHV1_180055 | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.659 |
truA | yeaZ | TPHV1_240025 | TPHV1_20120 | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | Universal bacterial protein YeaZ. | 0.556 |
tsaD | CEM60679.1 | TPHV1_110092 | TPHV1_10347 | tRNA N6-adenosine threonylcarbamoyltransferase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Putative Sua5/YciO/YrdC/YwlC family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the SUA5 family. | 0.540 |
tsaD | tsaE | TPHV1_110092 | TPHV1_20121 | tRNA N6-adenosine threonylcarbamoyltransferase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | 0.970 |
tsaD | yeaZ | TPHV1_110092 | TPHV1_20120 | tRNA N6-adenosine threonylcarbamoyltransferase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Universal bacterial protein YeaZ. | 0.949 |