Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
CEM61588.1Adenylate/guanylate cyclase catalytic domain protein. (632 aa)    
Predicted Functional Partners:
CEM61784.1
Diguanylate cyclase (GGDEF) domain protein (fragment).
 
 
 0.949
CEM63218.1
Tetratricopeptide repeat protein.
 
 
 0.929
CEM61520.1
Putative adenylyl cyclase CyaB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
     
 0.911
CEM60750.1
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.900
nrdD
Anaerobic ribonucleoside-triphosphate reductase.
     
  0.900
CEM61310.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein (modular protein).
 
 
 0.882
cheR-2
CheR methyltransferase, SAM binding domain protein.
  
 
 0.842
CEM61320.1
Cyclic nucleotide-binding domain protein.
 
 
 0.830
CEM61102.1
Diguanylate cyclase (GGDEF) domain protein.
 
 
 0.820
CEM63210.1
Cyclic nucleotide-binding domain protein.
 
 
 0.816
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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