STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEM61588.1Adenylate/guanylate cyclase catalytic domain protein. (632 aa)    
Predicted Functional Partners:
CEM61784.1
Diguanylate cyclase (GGDEF) domain protein (fragment).
 
 
 0.959
CEM63218.1
Tetratricopeptide repeat protein.
 
 
 0.930
CEM61310.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein (modular protein).
 
 0.922
CEM61520.1
Putative adenylyl cyclase CyaB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
     
 0.910
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.908
CEM60750.1
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.901
nrdD
Anaerobic ribonucleoside-triphosphate reductase.
     
  0.900
cheR-2
CheR methyltransferase, SAM binding domain protein.
  
 
 0.890
CEM61320.1
Cyclic nucleotide-binding domain protein.
 
 
 0.831
CEM61102.1
Diguanylate cyclase (GGDEF) domain protein.
 
 0.829
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.