Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CEM61629.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (118 aa)    
Predicted Functional Partners:
CEM62560.1
PTS system, beta-glucoside-specific, IIABC component.
  
 
 0.915
mtlA
PTS system mannitol-specific EIICBA component (Includes: Mannitol permease IIC component; Mannitol-specific phosphotransferase enzyme IIB component; Mannitol-specific phosphotransferase enzyme IIA component).
  
  
 0.849
fruA
PTS system fructose-specific EIIABC component.
  
  
 0.677
fruA-2
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; PTS system fructose-specific EIIABC component (Includes: Fructose-specific phosphotransferase enzyme IIA component; Fructose-specific phosphotransferase enzyme IIB component; Fructose permease IIC component).
  
  
 0.677
CEM61963.1
Putative Protein-N(pi)-phosphohistidine--sugar phosphotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.646
CEM61628.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
       0.636
php
Putative hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.583
CEM61626.1
Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function.
       0.583
yhfU
Hypothetical protein; No homology to any previously reported sequences.
       0.583
CEM61630.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
     
 0.536
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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