STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdxB-24-phosphoerythronate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa)    
Predicted Functional Partners:
gpmA
Phosphoglyceromutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 0.930
CEM60437.1
Phosphoribulokinase/uridine kinase family protein.
   
 0.807
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
   0.676
CEM61578.1
Putative threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.655
CEM62930.1
Putative threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.655
rplP
50S ribosomal subunit protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
   
   0.630
rplB
50S ribosomal subunit protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
    
   0.618
rplV
50S ribosomal subunit protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
    
 
 0.617
adhE
Fused acetaldehyde-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.605
rplQ
50S ribosomal subunit protein L17; Function of homologous gene experimentally demonstrated in an other organism; structure.
   
   0.598
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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