STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEM62013.15-amino-6-(5-phosphoribosylamino)uracil reductase. (238 aa)    
Predicted Functional Partners:
ribBA
Riboflavin biosynthesis protein RibBA (Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.923
ribE-2
Riboflavin synthase.
  
  
 0.829
adhR
HTH-type transcriptional regulator AdhR (fragment).
     
 0.795
CEM62012.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
 
     0.766
ribE
Riboflavin synthase beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
 
 0.587
CEM62587.1
Putative ankyrin repeat-containing protein TP_0502; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.541
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
  0.540
CEM62891.1
Inosine 5-monophosphate dehydrogenase.
  
  
 0.505
nadE
NAD+ synthase; Belongs to the NAD synthetase family.
  
  
 0.461
CEM63123.1
Ankyrin repeat protein.
  
 
 0.444
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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