STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adhRHTH-type transcriptional regulator AdhR (fragment). (79 aa)    
Predicted Functional Partners:
CEM61005.1
Pyridine nucleotide-disulfide oxidoreductase (fragment).
  
 
 0.818
dnaJ
Chaperone Hsp40, co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...]
  
 
 0.796
CEM61039.1
DnaJ domain protein.
  
 
 0.796
CEM61313.1
DnaJ domain protein.
  
 
 0.796
CEM62975.1
DnaJ domain protein.
  
 
 0.796
CEM62013.1
5-amino-6-(5-phosphoribosylamino)uracil reductase.
     
 0.795
CEM62012.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
       0.756
CEM61310.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein (modular protein).
   
 
 0.754
CEM61784.1
Diguanylate cyclase (GGDEF) domain protein (fragment).
  
 
 0.748
CEM62038.1
7TM diverse intracellular signaling (fragment).
   
 
 0.743
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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