Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
CEM62085.1ATPase, AAA family. (732 aa)    
Predicted Functional Partners:
ymdB
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
   0.901
dnaN
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 
 0.788
CEM62086.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
       0.773
CEM62087.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
       0.773
CEM61386.1
ATP-dependent DNA helicase, RecQ family.
 
 
 
 0.756
recQ
ATP-dependent DNA helicase RecQ.
 
 
 
 0.740
nadE
NAD+ synthase; Belongs to the NAD synthetase family.
  
    0.714
CEM61010.1
HAD hydrolase, family IIA; Belongs to the HAD-like hydrolase superfamily.
 
      0.583
folD
Bifunctional protein FolD (Includes: Methylenetetrahydrofolate dehydrogenase; Methenyltetrahydrofolate cyclohydrolase).
     
 0.565
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
 
 0.534
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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