STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEM62098.1Putative GTP cyclohydrolase 1 type 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (257 aa)    
Predicted Functional Partners:
lspA
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
 
     0.793
CEM62097.1
Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function.
       0.773
CEM62100.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
       0.750
CEM63457.1
Tetratricopeptide repeat protein.
   
    0.726
ydeL
Uncharacterized HTH-type transcriptional regulator YdeL.
  
    0.634
rmlB
dTDP-glucose 4,6 dehydratase, NAD(P)-binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
    0.605
CEM61296.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.532
metG
Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.453
CEM61173.1
Putative zinc ribbon domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.450
pepT
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
  
    0.431
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
Server load: low (28%) [HD]