Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CEM62254.1NQR2/RnfD/RnfE family protein. (342 aa)    
Predicted Functional Partners:
CEM62255.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
 
 0.989
rnfE
Electron transport complex, RnfABCDGE type, E subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
 
 
 0.974
rnfG
Electron transport complex, RnfABCDGE type, G subunit.
 
 
 0.973
rnfC
Electron transport complex, RnfABCDGE type, C subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
 
 
 0.960
rsxA
Putative inner membrane subunit of an electron transport system; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
 
 
 0.934
rnfB
Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
 
 
 0.929
nifJ
Pyruvate-flavodoxin oxidoreductase.
   
 
 0.854
CEM62257.1
Divergent PAP2 family.
     
 0.782
CEM62252.1
Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function.
     
 0.777
CEM62253.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
       0.773
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.