Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CEM62258.1Pseudouridine synthase, RluA family; Belongs to the pseudouridine synthase RluA family. (312 aa)    
Predicted Functional Partners:
CEM62259.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
     
 0.819
CEM60739.1
Pseudouridine synthase.
  
     0.761
CEM61936.1
Pseudouridine synthase, RluA family.
  
     0.757
CEM61788.1
Pseudouridine synthase.
  
     0.667
obg
GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
 
 
 0.645
CEM62260.1
Hypothetical protein; No homology to any previously reported sequences.
       0.631
rplC
50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
 
 
 
 0.585
rplM
50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
 
 
 0.563
CEM62252.1
Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function.
       0.551
CEM62253.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
       0.551
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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