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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ltaAL-allo-threonine aldolase. (363 aa)    
Predicted Functional Partners:
ilvA
Threonine ammonia-lyase.
   
 
 0.934
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 0.925
CEM61578.1
Putative threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 0.921
CEM62930.1
Putative threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 0.921
CEM62569.1
Beta-eliminating lyase.
     
  0.900
ychF
Putative GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
      0.869
CEM62269.1
Cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
       0.773
CEM62268.1
Phospholipase, patatin family.
       0.739
CEM62267.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.727
CEM62266.1
Hypothetical protein; No homology to any previously reported sequences.
       0.449
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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