Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (396 aa)    
Predicted Functional Partners:
pta
Phosphate acetyltransferase.
 
 
 0.997
ywdH
Putative aldehyde dehydrogenase YwdH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the aldehyde dehydrogenase family.
    
 0.917
acyP
Acylphosphatase.
     
 0.915
ydbK
Putative 2-oxoacid-flavodoxin fused oxidoreductase:conserved protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.862
nifJ
Pyruvate-flavodoxin oxidoreductase.
     
 0.824
CEM62560.1
PTS system, beta-glucoside-specific, IIABC component.
     
 0.780
CEM61966.1
Rubredoxin.
     
 0.577
fruA
PTS system fructose-specific EIIABC component.
   
  
 0.576
fruA-2
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; PTS system fructose-specific EIIABC component (Includes: Fructose-specific phosphotransferase enzyme IIA component; Fructose-specific phosphotransferase enzyme IIB component; Fructose permease IIC component).
   
  
 0.576
CEM61963.1
Putative Protein-N(pi)-phosphohistidine--sugar phosphotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.513
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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