Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CEM62344.1Tetratricopeptide repeat protein. (315 aa)    
Predicted Functional Partners:
greA
Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
       0.801
CEM60452.1
Peptidyl-prolyl cis-trans isomerase.
  
 0.788
CEM62342.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
       0.675
CEM62347.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
   
 0.569
CEM62345.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.566
htpG
Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.
  
 0.458
CEM60933.1
WD domain, G-beta repeat protein.
   
 0.456
alaS
Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.439
CEM60657.1
LysM domain protein.
  
 0.435
dnaK
Chaperone Hsp70, co-chaperone with DnaJ; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.429
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.