Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CEM62560.1PTS system, beta-glucoside-specific, IIABC component. (628 aa)    
Predicted Functional Partners:
fruA-2
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; PTS system fructose-specific EIIABC component (Includes: Fructose-specific phosphotransferase enzyme IIA component; Fructose-specific phosphotransferase enzyme IIB component; Fructose permease IIC component).
 
  
 0.992
bglA
Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glycosyl hydrolase 1 family.
  
 0.992
fruA
PTS system fructose-specific EIIABC component.
 
  
 0.991
ptsH
Phosphocarrier protein HPr.
  
 0.979
ptsH-2
Phosphocarrier protein HPr.
  
 0.979
ptsH-3
Phosphocarrier protein HPr.
  
 0.979
ptsI
PEP-protein phosphotransferase of PTS system (enzyme I); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.977
CEM61963.1
Putative Protein-N(pi)-phosphohistidine--sugar phosphotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
0.976
CEM60392.1
Glycosyl hydrolase family 20, catalytic domain protein.
  
  
 0.974
CEM60663.1
Glycosyl hydrolase family 20, catalytic domain protein.
  
  
 0.974
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.