CEM62569.1 protein (Treponema phagedenis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CEM62569.1

Beta-eliminating lyase. (345 aa)

Predicted Functional Partners:

ilvA

0.934

glyA

0.933

CEM61578.1

0.922

CEM62930.1

0.922

ltaA

0.900

CEM62568.1

0.578

CEM62570.1

0.422

Your Current Organism:

Treponema phagedenis

NCBI taxonomy Id: 162
Other names: T. phagedenis

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEM61578.1	CEM62569.1	TPHV1_20115	TPHV1_40072	Putative threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	Beta-eliminating lyase.	0.922
CEM61578.1	CEM62930.1	TPHV1_20115	TPHV1_500040	Putative threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	Putative threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	0.928
CEM61578.1	ilvA	TPHV1_20115	TPHV1_50043	Putative threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	Threonine ammonia-lyase.	0.952
CEM61578.1	ltaA	TPHV1_20115	TPHV1_30165	Putative threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	L-allo-threonine aldolase.	0.922
CEM62568.1	CEM62569.1	TPHV1_40071	TPHV1_40072	Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.	Beta-eliminating lyase.	0.578
CEM62569.1	CEM61578.1	TPHV1_40072	TPHV1_20115	Beta-eliminating lyase.	Putative threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	0.922
CEM62569.1	CEM62568.1	TPHV1_40072	TPHV1_40071	Beta-eliminating lyase.	Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.	0.578
CEM62569.1	CEM62570.1	TPHV1_40072	TPHV1_40073	Beta-eliminating lyase.	Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.	0.422
CEM62569.1	CEM62930.1	TPHV1_40072	TPHV1_500040	Beta-eliminating lyase.	Putative threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	0.922
CEM62569.1	glyA	TPHV1_40072	TPHV1_10035	Beta-eliminating lyase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.933
CEM62569.1	ilvA	TPHV1_40072	TPHV1_50043	Beta-eliminating lyase.	Threonine ammonia-lyase.	0.934
CEM62569.1	ltaA	TPHV1_40072	TPHV1_30165	Beta-eliminating lyase.	L-allo-threonine aldolase.	0.900
CEM62570.1	CEM62569.1	TPHV1_40073	TPHV1_40072	Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.	Beta-eliminating lyase.	0.422
CEM62930.1	CEM61578.1	TPHV1_500040	TPHV1_20115	Putative threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	Putative threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	0.928
CEM62930.1	CEM62569.1	TPHV1_500040	TPHV1_40072	Putative threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	Beta-eliminating lyase.	0.922
CEM62930.1	ilvA	TPHV1_500040	TPHV1_50043	Putative threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	Threonine ammonia-lyase.	0.952
CEM62930.1	ltaA	TPHV1_500040	TPHV1_30165	Putative threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	L-allo-threonine aldolase.	0.922
glyA	CEM62569.1	TPHV1_10035	TPHV1_40072	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Beta-eliminating lyase.	0.933
glyA	ilvA	TPHV1_10035	TPHV1_50043	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Threonine ammonia-lyase.	0.935
glyA	ltaA	TPHV1_10035	TPHV1_30165	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	L-allo-threonine aldolase.	0.933