Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CEM62589.1Penicillin-binding protein, 1A family. (909 aa)    
Predicted Functional Partners:
mrdA
Penicillin-binding protein 2.
 
 
 0.974
CEM62999.1
Penicillin-binding protein, transpeptidase domain protein.
 
 
 0.961
CEM60662.1
Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family.
  
  
 0.941
CEM61628.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
     
 0.912
CEM61834.1
Beta-lactamase.
     
 0.912
CEM61828.1
Serine-type D-Ala-D-Ala carboxypeptidase.
     
  0.900
CEM62591.1
Peptidase, M23 family.
 
   
 0.801
mrdB
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
   
 0.736
CEM63299.1
Peptidase, M23 family.
  
   
 0.712
CEM62993.1
Peptidase, M23 family.
 
   
 0.701
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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