Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CEM62627.1Stage II sporulation protein E. (553 aa)    
Predicted Functional Partners:
CEM61310.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein (modular protein).
 
  
 0.983
CEM61784.1
Diguanylate cyclase (GGDEF) domain protein (fragment).
  
 
 0.982
CEM62626.1
Anti-sigma factor antagonist; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.979
CEM62625.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
 
 0.953
CEM62362.1
Anti-sigma factor antagonist; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.947
CEM61007.1
Response regulator receiver domain protein.
  
 
 0.866
CEM61785.1
Diguanylate cyclase (GGDEF) domain protein (fragment).
  
  
 0.820
CEM61826.1
Anti-sigma factor antagonist; Belongs to the anti-sigma-factor antagonist family.
  
 
 0.787
CEM63082.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
   
    0.741
CEM61588.1
Adenylate/guanylate cyclase catalytic domain protein.
 
 
 0.711
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.