Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
CEM62629.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (314 aa)    
Predicted Functional Partners:
CEM62630.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
     0.956
CEM62631.1
Tetratricopeptide repeat protein.
 
     0.832
CEM62628.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.732
CEM61580.1
Alpha amylase, catalytic domain protein.
 
  
 0.681
CEM62632.1
Tetratricopeptide repeat protein.
 
     0.638
ogt
Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
  
 0.632
CEM61816.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
 
   
 0.622
CEM62633.1
Tetratricopeptide repeat protein (modular protein).
  
  
 0.574
greA
Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
  
   
 0.518
CEM62341.1
Putative ribosomal subunit interface protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.504
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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