STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEM62674.15-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (214 aa)    
Predicted Functional Partners:
folD
Bifunctional protein FolD (Includes: Methylenetetrahydrofolate dehydrogenase; Methenyltetrahydrofolate cyclohydrolase).
    
 0.940
CEM61137.1
Formiminotransferase-cyclodeaminase.
    
 0.927
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
    
 0.918
ftcD
Glutamate formimidoyltransferase.
     
  0.900
CEM60912.1
Peptidase, S54 family.
  
    0.649
CEM61960.1
Peptidase, S54 family.
  
    0.649
groS
10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
 
   
 0.507
CEM62673.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.488
folA
Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
 
   
 0.441
moaC
Molybdopterin biosynthesis, protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
     
 0.427
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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