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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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cobBNAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. (249 aa)    
Predicted Functional Partners:
nadE
NAD+ synthase; Belongs to the NAD synthetase family.
    
 0.950
nadD
Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.938
deoD
Purine nucleoside phosphorylase DeoD-type.
    
 0.923
ppnK
Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.917
CEM60933.1
WD domain, G-beta repeat protein.
  
 0.798
gluD
NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.782
CEM62948.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
   
   0.774
CEM62391.1
Hypothetical protein; No homology to any previously reported sequences.
    
  0.716
recQ
ATP-dependent DNA helicase RecQ.
  
 
 0.664
CEM61386.1
ATP-dependent DNA helicase, RecQ family.
  
 
 0.664
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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