Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CEM62911.1HAMP domain protein. (715 aa)    
Predicted Functional Partners:
cheA
Chemotaxis protein CheA.
 
 0.977
cheR-2
CheR methyltransferase, SAM binding domain protein.
 
 0.974
cheW
Chemotaxis protein CheW.
 
 0.957
cheB
Fused chemotaxis regulator; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.940
cheR
CheR methyltransferase, SAM binding domain protein.
 
 0.933
cheY
Chemotaxis protein CheY.
 
  
 0.777
CEM61784.1
Diguanylate cyclase (GGDEF) domain protein (fragment).
  
 
 0.602
asnS
Asparaginyl tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.578
CEM61310.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein (modular protein).
  
 
 0.473
fliN
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
 
 
 0.422
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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