Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CEM62754.1HD domain protein. (426 aa)    
Predicted Functional Partners:
CEM60911.1
Diguanylate cyclase (GGDEF) domain protein.
 
 0.946
CEM62755.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0102 family.
      0.913
CEM61784.1
Diguanylate cyclase (GGDEF) domain protein (fragment).
 
 
 0.878
CEM61785.1
Diguanylate cyclase (GGDEF) domain protein (fragment).
 
  
 0.805
CEM62757.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
   
   0.795
CEM62756.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.773
CEM61101.1
Diguanylate cyclase (GGDEF) domain protein.
 
 
 0.769
CEM61102.1
Diguanylate cyclase (GGDEF) domain protein.
 
 
 0.742
rplS
50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
   0.705
rimM
Ribosome maturation factor RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
       0.679
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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