Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CEM62770.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (100 aa)    
Predicted Functional Partners:
CEM62771.1
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
       0.773
CEM61500.1
Hypothetical protein; No homology to any previously reported sequences.
  
     0.585
CEM62772.1
Transcriptional regulator, LacI family.
       0.548
CEM62773.1
Beta-1,4-mannooligosaccharide phosphorylase.
       0.548
CEM62058.1
Phosphoribosylformylglycinamidine synthase.
     
 0.514
CEM61299.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.508
metK
Methionine adenosyltransferase 1; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.471
argR
Arginine repressor; Regulates arginine biosynthesis genes.
 
  
 0.437
CEM61441.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.430
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.410
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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