Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CEM62772.1Transcriptional regulator, LacI family. (346 aa)    
Predicted Functional Partners:
CEM62773.1
Beta-1,4-mannooligosaccharide phosphorylase.
 
     0.889
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 
 0.678
ptsH
Phosphocarrier protein HPr.
   
 
 0.581
ptsH-2
Phosphocarrier protein HPr.
   
 
 0.581
ptsH-3
Phosphocarrier protein HPr.
   
 
 0.581
CEM62891.1
Inosine 5-monophosphate dehydrogenase.
    
 
 0.576
ribBA
Riboflavin biosynthesis protein RibBA (Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
   0.553
CEM62770.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.548
CEM62771.1
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
       0.548
CEM62774.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
 
   
 0.540
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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