Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cmkCytidylate kinase. (189 aa)    
Predicted Functional Partners:
nrdA
Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
    
  0.901
CEM60437.1
Phosphoribulokinase/uridine kinase family protein.
    
  0.900
CEM62148.1
Cytidine and deoxycytidylate deaminase zinc-binding region.
     
  0.900
nadN
Putative 5'-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 5'-nucleotidase family.
     
  0.900
surE
5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
nrdB
Ribonucleoside-diphosphate reductase subunit beta.
     
  0.900
CEM62799.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
     0.801
upp
Putative uracil phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
  0.791
CEM63003.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.760
pheS
Phenylalanine--tRNA ligase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
 
     0.750
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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