node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CEM62672.1 | CEM62799.1 | TPHV1_40175 | TPHV1_50059 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.860 |
CEM62672.1 | exoA | TPHV1_40175 | TPHV1_240011 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Exodeoxyribonuclease. | 0.809 |
CEM62672.1 | polA | TPHV1_40175 | TPHV1_80113 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.429 |
CEM62797.1 | CEM62799.1 | TPHV1_50057 | TPHV1_50059 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.592 |
CEM62797.1 | cmk | TPHV1_50057 | TPHV1_50058 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Cytidylate kinase. | 0.663 |
CEM62797.1 | murC | TPHV1_50057 | TPHV1_50056 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.771 |
CEM62799.1 | CEM62672.1 | TPHV1_50059 | TPHV1_40175 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.860 |
CEM62799.1 | CEM62797.1 | TPHV1_50059 | TPHV1_50057 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.592 |
CEM62799.1 | cmk | TPHV1_50059 | TPHV1_50058 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Cytidylate kinase. | 0.802 |
CEM62799.1 | dinB | TPHV1_50059 | TPHV1_510040 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.561 |
CEM62799.1 | dnaN | TPHV1_50059 | TPHV1_20004 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.601 |
CEM62799.1 | exoA | TPHV1_50059 | TPHV1_240011 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Exodeoxyribonuclease. | 0.875 |
CEM62799.1 | murC | TPHV1_50059 | TPHV1_50056 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.556 |
CEM62799.1 | nth | TPHV1_50059 | TPHV1_140030 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.500 |
CEM62799.1 | polA | TPHV1_50059 | TPHV1_80113 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.513 |
CEM62799.1 | uvrB | TPHV1_50059 | TPHV1_50053 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Excinulease of nucleotide excision repair, DNA damage recognition component; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. I [...] | 0.519 |
cmk | CEM62797.1 | TPHV1_50058 | TPHV1_50057 | Cytidylate kinase. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.663 |
cmk | CEM62799.1 | TPHV1_50058 | TPHV1_50059 | Cytidylate kinase. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.802 |
cmk | murC | TPHV1_50058 | TPHV1_50056 | Cytidylate kinase. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.633 |
dinB | CEM62799.1 | TPHV1_510040 | TPHV1_50059 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.561 |