Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mgtAMagnesium-importing ATPase. (719 aa)    
Predicted Functional Partners:
CEM62885.1
Hypothetical protein; No homology to any previously reported sequences.
     0.987
CEM62883.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.709
CEM60930.1
Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function.
  
 
 0.597
adhE
Fused acetaldehyde-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.530
CEM61522.1
FG-GAP repeat protein.
   
 
 0.505
rpsH
30S ribosomal subunit protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
    
   0.462
CEM63438.1
AAA-like domain protein.
   
    0.457
rpsM
30S ribosomal subunit protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.
   
   0.424
CEM60615.1
PAP2 family protein.
 
 
 0.415
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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