node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CEM60452.1 | dinB | TPHV1_10120 | TPHV1_510040 | Peptidyl-prolyl cis-trans isomerase. | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.766 |
CEM60452.1 | nifJ | TPHV1_10120 | TPHV1_50039 | Peptidyl-prolyl cis-trans isomerase. | Pyruvate-flavodoxin oxidoreductase. | 0.733 |
CEM60452.1 | polA | TPHV1_10120 | TPHV1_80113 | Peptidyl-prolyl cis-trans isomerase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.608 |
CEM62215.1 | dinB | TPHV1_30110 | TPHV1_510040 | Peptidase S24-like protein. | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.839 |
CEM62215.1 | dnaE | TPHV1_30110 | TPHV1_10045 | Peptidase S24-like protein. | DNA polymerase III subunit alpha. | 0.427 |
CEM62215.1 | polA | TPHV1_30110 | TPHV1_80113 | Peptidase S24-like protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.523 |
CEM62215.1 | recA | TPHV1_30110 | TPHV1_40193 | Peptidase S24-like protein. | DNA strand exchange and recombination protein with protease and nuclease activity; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.973 |
CEM62974.1 | dinB | TPHV1_510041 | TPHV1_510040 | Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function. | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.793 |
CEM63120.1 | dinB | TPHV1_60108 | TPHV1_510040 | DNA polymerase III domain protein. | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.783 |
CEM63120.1 | dnaE | TPHV1_60108 | TPHV1_10045 | DNA polymerase III domain protein. | DNA polymerase III subunit alpha. | 0.981 |
CEM63120.1 | dnaN | TPHV1_60108 | TPHV1_20004 | DNA polymerase III domain protein. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.996 |
CEM63120.1 | polA | TPHV1_60108 | TPHV1_80113 | DNA polymerase III domain protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.947 |
CEM63120.1 | recA | TPHV1_60108 | TPHV1_40193 | DNA polymerase III domain protein. | DNA strand exchange and recombination protein with protease and nuclease activity; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.548 |
dinB | CEM60452.1 | TPHV1_510040 | TPHV1_10120 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Peptidyl-prolyl cis-trans isomerase. | 0.766 |
dinB | CEM62215.1 | TPHV1_510040 | TPHV1_30110 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Peptidase S24-like protein. | 0.839 |
dinB | CEM62974.1 | TPHV1_510040 | TPHV1_510041 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function. | 0.793 |
dinB | CEM63120.1 | TPHV1_510040 | TPHV1_60108 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase III domain protein. | 0.783 |
dinB | dnaE | TPHV1_510040 | TPHV1_10045 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase III subunit alpha. | 0.845 |
dinB | dnaN | TPHV1_510040 | TPHV1_20004 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.949 |
dinB | nifJ | TPHV1_510040 | TPHV1_50039 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Pyruvate-flavodoxin oxidoreductase. | 0.793 |