| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ddl | murC | TPHV1_190028 | TPHV1_50056 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.992 |
| ddl | murD | TPHV1_190028 | TPHV1_20168 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.973 |
| ddl | murF | TPHV1_190028 | TPHV1_110035 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.993 |
| ddl | murI | TPHV1_190028 | TPHV1_60082 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.657 |
| glsA | gluD | TPHV1_10008 | TPHV1_30169 | Glutaminase; Belongs to the glutaminase family. | NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.915 |
| glsA | murD | TPHV1_10008 | TPHV1_20168 | Glutaminase; Belongs to the glutaminase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.912 |
| glsA | murI | TPHV1_10008 | TPHV1_60082 | Glutaminase; Belongs to the glutaminase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.916 |
| glsA | sudA | TPHV1_10008 | TPHV1_220043 | Glutaminase; Belongs to the glutaminase family. | Sulfide dehydrogenase subunit alpha. | 0.908 |
| gluD | glsA | TPHV1_30169 | TPHV1_10008 | NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutaminase; Belongs to the glutaminase family. | 0.915 |
| gluD | murI | TPHV1_30169 | TPHV1_60082 | NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.863 |
| gluD | sudA | TPHV1_30169 | TPHV1_220043 | NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Sulfide dehydrogenase subunit alpha. | 0.915 |
| murC | ddl | TPHV1_50056 | TPHV1_190028 | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.992 |
| murC | murD | TPHV1_50056 | TPHV1_20168 | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.999 |
| murC | murF | TPHV1_50056 | TPHV1_110035 | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.953 |
| murC | murI | TPHV1_50056 | TPHV1_60082 | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.610 |
| murD | ddl | TPHV1_20168 | TPHV1_190028 | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.973 |
| murD | glsA | TPHV1_20168 | TPHV1_10008 | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Glutaminase; Belongs to the glutaminase family. | 0.912 |
| murD | murC | TPHV1_20168 | TPHV1_50056 | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.999 |
| murD | murF | TPHV1_20168 | TPHV1_110035 | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.972 |
| murD | murI | TPHV1_20168 | TPHV1_60082 | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.938 |