STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEM63095.1Pentapeptide repeat family protein. (175 aa)    
Predicted Functional Partners:
CEM63096.1
Metallo-beta-lactamase domain protein.
   
 
 0.831
CEM63097.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.773
CEM61592.1
OmpA family protein.
 
 
 0.734
CEM63003.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.689
upp
Putative uracil phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
    0.668
CEM61762.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
     0.663
CEM62964.1
LysM domain protein.
   
 
 0.638
CEM62056.1
Phosphoribosyl transferase domain protein.
  
     0.632
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.614
parE
DNA topoisomerase 4 subunit B.
   
 
 0.614
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.