STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEM63116.1Thiamine diphosphokinase. (221 aa)    
Predicted Functional Partners:
rsgA
Putative ribosome biogenesis GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
  
 
 0.930
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.907
CEM63061.1
Alkaline phosphatase family protein; Belongs to the alkaline phosphatase family.
     
  0.900
atoC
Fused response regulator of ato opeon, in two-component system with AtoS: response regulator; Function of homologous gene experimentally demonstrated in an other organism; regulator.
       0.773
CEM63118.1
PAS domain S-box protein.
       0.773
nifJ
Pyruvate-flavodoxin oxidoreductase.
   
   0.725
flgK
Flagellar hook-associated protein FlgK.
   
   0.695
flaB-2
Flagellar filament 31 kDa core protein; Component of the core of the flagella. Belongs to the bacterial flagellin family.
   
   0.691
CEM63119.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.555
ydbK
Putative 2-oxoacid-flavodoxin fused oxidoreductase:conserved protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
   0.507
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.