Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
atoCFused response regulator of ato opeon, in two-component system with AtoS: response regulator; Function of homologous gene experimentally demonstrated in an other organism; regulator. (456 aa)    
Predicted Functional Partners:
CEM63118.1
PAS domain S-box protein.
 
 0.950
fliN
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
  
  
 0.927
CEM61784.1
Diguanylate cyclase (GGDEF) domain protein (fragment).
  
 
 0.877
CEM61310.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein (modular protein).
 
 
0.852
rpoN
RNA polymerase sigma-54 factor.
 
   
 0.836
fliM
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
  
  
 0.800
CEM63116.1
Thiamine diphosphokinase.
       0.773
fliP
Flagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
  
  
 0.767
fliH
Flagellar assembly protein FliH.
 
  
 0.740
CEM63331.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
  
 0.723
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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