Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CEM63147.1Cys/Met metabolism PLP-dependent enzyme (modular protein). (429 aa)    
Predicted Functional Partners:
metA
Aspartokinase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
 
 
 0.995
CEM63143.1
Homoserine dehydrogenase.
 
 
 0.957
mdeA
Methionine gamma-lyase.
 
 
0.940
hly
Hemolysin.
   
 0.931
metK
Methionine adenosyltransferase 1; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.920
ilvA
Threonine ammonia-lyase.
   
 
  0.809
asd
Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
  
 0.685
CEM63087.1
Pyridine nucleotide-disulfide oxidoreductase (fragment).
  
  
 0.663
CEM60523.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
  
 0.647
CEM63085.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
    0.634
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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