STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nnrEYjeF domain protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] (496 aa)    
Predicted Functional Partners:
CEM61264.1
Hydrolase, NUDIX family.
  
 0.958
CEM60834.1
DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
  
 0.881
CEM61224.1
ATP-dependent RNA helicase RhlB (modular protein); Belongs to the DEAD box helicase family.
  
 0.881
CEM62159.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
 0.881
CEM63181.1
DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
  
 0.881
groL
Cpn60 chaperonin GroEL, large subunit of GroESL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
   0.821
tsaE
tRNA threonylcarbamoyladenosine biosynthesis protein TsaE.
  
 
 0.761
nifJ
Pyruvate-flavodoxin oxidoreductase.
  
   0.746
glgX
Glycogen operon protein GlgX homolog; Belongs to the glycosyl hydrolase 13 family.
  
    0.665
nrdA
Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
     
 0.651
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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